FIELD: organic chemistry, medicine. SUBSTANCE: desired product is prepared by reaction of 5,7-dimethyl-6-oxo-1,3-diazadamanthane with dichloride of phenyl phosphoric acid in the presence of triethylamine, molar ratio being 1.0:(0.8-1.5):(2.0-6.0). The process is carried out by mixing within 4 h at room temperature in the medium of organic solvent. Desired product having essential formula C15H19N2O3P and melting point 193-194 C is prepared by yield 80-83.2 Proposed method enables to increase yield of desired product by 23-41 EFFECT: simplifies the method, increases yield of desired product. 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| 2-BIS-(β- CHLOROETHYL)- AMINO- OR 2-PHENOXY -5,7-DIMETHYL -2,6-DIOXO- 1,3-DIAZA -2-PHOSPHAADAMANTANES SHOWING ANTITUMOR ACTIVITY | 1985 |
|
SU1282521A1 |
| 2′, 2′, 5,7- TETRAMETHYL -6- OXOSPIRO- (1,4- DIAZAADAMANTANE -2,4′- TETRAHYDROPYRWNE) | 1984 |
|
SU1162195A1 |
| 2',2',5,7-TETRAMETHYL-6-OXOSPIRO-(1,3-DIAZAADAMANTANE- 2,4'-TETRAHYDROTHIOPYRAN POSSESSING ANTISTAPHYLOCOCCIC ACTIVITY | 1984 |
|
SU1246568A1 |
| PROCESS FOR THE PREPARATION OF DICHLOROANHYDRIDES OF CHLORINE-CONTAINING 1,3-BUTADIENE-2-PHOSPHONIC ACIDS | 0 |
|
SU681066A1 |
| I′-BENZYL-5,7-DIMETHYL-6-OXOSPIRO-(1,3-DIAZADAMANTANE- 2,4′-PIPERIDINE POSSESSING α-ADRENOBLOCKING ACTIVITY | 1984 |
|
SU1221878A1 |
| 1,3-DISUBSTITUTED (2-THIO)'UREAS HAVING EFFECT ON MNESTIC PROCESSES | 0 |
|
SU1097622A1 |
| PROCESS FOR PRODUCING MONOMETHYLCYANINE DYES OF THE 1,3-DIMETHYL-1,3-DIHYDROPYRIMIDONE-2 SERIES | 0 |
|
SU1004426A1 |
| METHOD OF SYNTHESIS OF SUBSTITUTED 1(2)-BENZYL-5-R-TETRAZOLES | 1991 |
|
RU2030407C1 |
| METHOD OF PREPARING BENZOMORPHANES OR THEIR SALTS OR RACEMIC MIXTURE OR THEIR OPTICAL ISOMERS | 0 |
|
SU721002A3 |
| METHOD OF OBTAINING DERIVATIVES OF BENZOXAZINE-2-ON | 0 |
|
SU1138025A3 |
