VALINEAMIDE DERIVATIVES AS RACEMATE OR AS R(+) CONFIGURATION OF L-ISOMER HAVING FUNGICIDAL ACTIVITY Russian patent published in 1994 - IPC

FIELD: used as a biologically active agent. SUBSTANCE: the product: valine derivatives of the general formula: wherein R₁ is iso-Pr, sec-Bu; R₂ is Cl, CH₃, C₂H₅, CH₃O as a racemate or as a R(+) configuration of L-isomer. Reagent: or its reactive derivative. Reagent 2: . Reaction conditions: in an organic solvent ((CH₂Cl₂)) in the presence of N-methylpiperidine at a temperature of not higher than -15 C for 27 hr followed by stirring at about ~ 20 C for 15 hr. EFFECT: improved properties of the valine derivatives. 3 tbl