FIELD: organic chemistry. SUBSTANCE: product - 5-chloro-2-pyridylamide-4-nitro-N-(carboxymethyl)-anthranilic acid, empirical formula is C12H8O3N3Cl, m. p. is 162-163 C, yield is 79%. Reagent 1: 5-chloro-3-pyridylamide-2-chloro-4-nitrobenzoic acid. Reagent 2: glycine. Reaction conditions: dimethylformamide, sodium carbonate. EFFECT: improved method of synthesis. 4 tbl
Title | Year | Author | Number |
---|---|---|---|
2,4-DICHLORO-5-NITROBENZOATE-2-PYRIDYL AMMODIUM HAVING ANALGETIC ACTIVITY | 1991 |
|
RU2039045C1 |
AGENT SHOWING ANALGETIC EFFECT | 1994 |
|
RU2101011C1 |
N-(3'-CHLOROBUTENE-2'-YL)ANTHRANILIC ACID ACIARYLAMIDES ELICITING ANTI-INFLAMMATORY ACTIVITY | 2000 |
|
RU2181718C2 |
N-(3'-CHLOROBUTENE-2'-YL)-ANTHRANILIC ACID AMIDE SHOWING ANTI-INFLAMMATORY ACTIVITY | 2000 |
|
RU2189377C2 |
MONOPOTASSIUM-DILITHIUM SALT OF GLYCYRRHIZIC ACID HAVING ANTIINFLAMMATORY AND ANTIULCEROUS ACTIVITY | 1987 |
|
SU1513881A1 |
ANTI-INFLAMMATORY ACTIVITY | 1999 |
|
RU2170726C1 |
N-(1,3-TIAZOL-2-YL)AMIDES OF 2-DIPHENYLMETHYLENEHYDRAZONO-5,5-DIMETHYL-2,4-DIOXOHEXANE ACID, DEMONSTRATING ANTI-INFLAMMATORY AND ANALGETIC ACTIVITY AND METHOD OF OBTAINING | 2007 |
|
RU2345072C1 |
N-(3'-CHLOROBUTENE-2'-YL)-ANTHRANILIC ACID ANILIDE ELICITING ANTI-INFLAMMATORY AND ANALGETIC ACTIVITY | 2000 |
|
RU2180657C1 |
NEW BIOLOGICALLY ACTIVE COMPOUND N-[3-(4-NITROPHENYLAMINO)-INDOL-2-YLMETHYLENE]AMINOGUANIDINE HYDROCHLORIDE WITH ANTIINFLAMMATORY ACTIVITY | 2010 |
|
RU2478618C2 |
N-ALLYLANTHRANILIC ACID AMIDE ELICITING ANTI-INFLAMMATORY, ANALGETIC AND ANTIHYPOXIC ACTIVITY | 2000 |
|
RU2180656C1 |
Authors
Dates
1994-12-15—Published
1991-11-18—Filed