FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to cis-isomers of N,N'=bis-(4-hydroxy-2,3,4,5- tetrahydrothiopene-3-yl)-di-amines of the formula (I) 
and their salts where a-g, i-m R is H; a-h X is O; a n = 3; b n = 4; c n = 5; d n = 6; e n = 7; f n = 8; g n = 9; h R is Ac, n = 6; i-o n = 6, for i X is disuccinate; k X is ditartrate; l X is diacetylsalicylate; m X is dehydroabietic acid 6-sulfoxylate; n X is glycyrrhizinate; o X is dichlorohydrate. Compounds show anti-inflammatory, antiulcer and analgetic activity. Compounds do not show toxicity and adverse effects that are characteristic for the known anti-inflammatory agents and can be obtained from available raw. EFFECT: improved medicinal properties of compounds. 7 tbl, 2 dwg, 21 ex
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