SALTS OF N,N-DIMETHYLAMINOETHYL-β-(4-HYDROXY-3,5-DI- TERT-BUTYLPHENYL) PROPIONATE AS CHOLINE ESTERASE INHIBITOR Russian patent published in 1995 - IPC

Abstract RU 2029760 C1

FIELD: as esterase inhibitor. SUBSTANCE: the product includes salts of N, N-dimethylaminoethyl-b-(4- hydroxy-3,5-di-tert-butylphenyl) propionate of the formula: wherein R is H, (C1-C16)Alk; X is CL, Br, J. Reagent 1: {3,5-[C(CH3)3]2-4-OH}C6H2CH2CH2COOCH3. Reagent 2: HOCH2CH2N(CH3)2 under alkaline catalysis conditions at 130-40 C in an argon current while removing the resulting methanol from the reaction zone and subsequently treating the resulting product with halohydrogen or alkylhalide in acetone, benzene or ether. EFFECT: improved properties of the title product. 1 tbl

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RU 2 029 760 C1

Authors

Nikiforov Grigorij Alekseevich

Braginskaja Faina Isaakovna

Ershov Vladimir Vladimirovich

Burlakova Elena Borisovna

Dates

1995-02-27Published

1992-07-31Filed