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Application

4952423/04, 1991-06-28

(22)

Actual filing date

1991-06-28

(45)

Published

1995-03-10

(72)

Inventor

Goleneva A.F.Prokhorova T.S.Nedugov A.N.Pavlova N.N.

(73)

Holder

Estestvenno-Nauchnyj Institut Pri Permskom Gosudarstvennom Universitete

1-METHOXY-1-(2-CHLOROPHENYLSELENO)ALKANES SHOWING ANTIINFLAMMATORY AND ANTIMICROBIAL ACTIVITY Russian patent published in 1995 - IPC

Abstract RU 2030399 C1

FIELD: organic chemistry. SUBSTANCE: product: 1-methoxy-(2-chlorophenylseleno)ethane, CH-O-CH(CH)-Se-C6H4-Cl-2, empirical formula is C9H11ClOSe, yield is 80% , b. p. is 113-115 C/2 mm mercury column. 1-Methoxy-1-(2-chlorophenylseleno)-2-methylpropane, CH-O-CH(izo-C3H7)Se-C6H4-Cl-2, empirical formula is C11H15ClOSe, m. p. is 147-149 C/3 mm mercury column, yield is 65%. Reagent 1: 2-chlorophenylselenomagnesium bromide. Reagent 2: chloromethyl or α-chloroisobutylmethyl ester. Reaction conditions: in diethyl ether, on water bath for 1 h. Synthesized compounds were used in medicine. EFFECT: improved method of synthesis. 2 tbl

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RU 2 030 399 C1

Authors

Goleneva A.F.

Prokhorova T.S.

Nedugov A.N.

Pavlova N.N.

Dates

1995-03-10—Published

1991-06-28—Filed

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