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2 034 856

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C1

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IPC

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Application

4786427/05, 1990-01-29

(22)

Actual filing date

1990-01-29

(45)

Published

1995-05-10

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Inventor

Iordanskaja L.I.Stotskaja L.L.Ulogova Ju.V.Krentsel' B.A.Gubajdulin L.Ju.Guryshev V.N.Starshinova I.V.Rusakov I.G.Shchitkov K.G.Sukhin G.M.Pecherskikh E.V.Chissov V.I.Kozlov A.M.Reznik L.V.Natochin Ju.V.Rastova N.V.Jur'Ev V.P.

(73)

Holder

Institut Neftekhimicheskogo Sinteza Im.A.V.Topchieva RanVsesojuznyj Nauchno-Issledovatel'Skij I Proektnyj Institut MonomerovMoskovskij Nauchno-Issledovatel'Skij Onkologicheskij Institut Im.P.A.Gertsena

COMPLEX COMPOUND OF CIS-DIAMMINOPLATINUM (II) WITH COPOLYMER OF MALEIC ACID SODIUM SALT AND 1,4-DIISOPROPOXYBUTENE-2 SHOWING ANTIMALIGNANT ACTIVITY AT THE BROAD RANGE OF THERAPEUTIC DOSES AT COMPLETE ABSENCE OF NEPHROTOXICITY AND IMMUNODEPRESSING ACTIONS Russian patent published in 1995 - IPC

Abstract RU 2034856 C1

FIELD: high-molecular compounds. SUBSTANCE: complex compound of cis-diamminoplatinum (II) with copolymer of maleic acid Na-salt shows broad range of therapeutic doses and absence of nephrotoxicity and immunodepressant action. EFFECT: increased effectiveness of compound proposed. 6 tbl

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RU 2 034 856 C1

Authors

Iordanskaja L.I.

Stotskaja L.L.

Ulogova Ju.V.

Krentsel' B.A.

Gubajdulin L.Ju.

Guryshev V.N.

Starshinova I.V.

Rusakov I.G.

Shchitkov K.G.

Sukhin G.M.

Pecherskikh E.V.

Chissov V.I.

Kozlov A.M.

Reznik L.V.

Natochin Ju.V.

Rastova N.V.

Jur'Ev V.P.

Dates

1995-05-10—Published

1990-01-29—Filed

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