METHOD OF OBTAINING ISOMERS OF AMMINEPLATINUM (II) DICHLORIDE FROM MAGNUS' SALT Russian patent published in 2008 - IPC C01G55/00 

Abstract RU 2329952 C1

FIELD: chemistry.

SUBSTANCE: can be used in medicine for obtaining antitumoral medical substances of the I and III generations. Magnus' salt is subjected to interaction with ammonium acetate when heated and at pH=5.4 for a period of an hour. Then concentrated hydrochloric acid, free from oxidizers is added to the cooled solution. The precipitated salt of cis-ammineplatinum (II) dichloride cis-[Pt(NH3)Cl2] is separated. The solution is further heated for a period of 1.5 hours and trans-ammineplatinum (II) dichloride.

EFFECT: increased output of these products.

4 tbl, 7 ex

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RU 2 329 952 C1

Authors

Starkov Aleksandr Konstantinovich

Kozhukhovskaja Galina Anatol'Evna

Dates

2008-07-27Published

2006-12-27Filed