FIELD: medicine. SUBSTANCE: prophylactic biopreparation has recombinant strain B. subtilis VKPM B-4759 as a basis and shows high antagonistic activity with respect to broad spectrum of pathogenic and opportunistic microorganisms, antiviral activity based on the interferon type α synthesis, and capability to induce g-interferon synthesis after peroral administration to animals. EFFECT: increased effectiveness of biopreparation proposed. 5 tbl
| Title | Year | Author | Number |
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| PROBIOTIC PREPARATION OF COMPLEX ACTION | 1999 |
|
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| DNA S54 FRAGMENT ENCODING POLYPEPTIDE SHOWING ACTIVITY OF GAMMA-INTERFERON, RECOMBINANT PLASMID DNA PROVIDING THE SYNTHESIS OF POLYPEPTIDE WITH ACTIVITY OF GAMMA-INTERFERON, AND THE STRAIN OF ESCHERICHIA COLI - A PRODUCER OF POLYPEPTIDE WITH GAMMA-INTERFERON ACTIVITY | 1992 |
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|
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RU2166323C2 |
