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IPC

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Application

98112850/13, 1998-06-30

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Start date

1998-06-30

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Actual filing date

1998-06-30

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Published

2001-08-20

(72)

Inventor

Beljavskaja V.A.Sorokulova Irina BorisovnaRomashova N.G.Kashperova T.A.Masycheva V.I.Il'Ichev A.A.Shchelkunov S.N.Daniljuk N.K.Nesterov A.E.Sandakhchiev L.S.Smirnov Valerij VeniaminovichPetrenko V.A.Krasnykh V.N.

(73)

Holder

Gosudarstvennyj Nauchnyj Tsentr Virusologii I Biotekhnologii

STRAIN OF BACTERIUM BACILLUS LICHENIFORMIS SHOWING ANTIVIRAL AND ANTIBACTERIAL ACTIVITY Russian patent published in 2001 - IPC

Abstract RU 2172343 C2

FIELD: medicinal microbiology. SUBSTANCE: invention relates to preparing probiotic strains. Cells of the strain Bacillus licheniformis 31 are transformed with plasmid pBMB 105 and a new recombinant strain Bacillus licheniformis 2336/105 is obtained. This strain is harmless for warm-blooded animals, it is able to inhibit pathogenic and opportunistic microflora and to produce alpha-2-interferon under microaerophilic conditions in the amount 102 IU/mg. Constructed strain can be used as a base for the new probiotic anti-infectious preparation. EFFECT: new strain indicated above, increased yield of alpha-2-interferon. 6 tbl, 4 ex

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RU 2 172 343 C2

Authors

Beljavskaja V.A.

Sorokulova Irina Borisovna

Romashova N.G.

Kashperova T.A.

Masycheva V.I.

Il'Ichev A.A.

Shchelkunov S.N.

Daniljuk N.K.

Nesterov A.E.

Sandakhchiev L.S.

Smirnov Valerij Veniaminovich

Petrenko V.A.

Krasnykh V.N.

Dates

2001-08-20—Published

1998-06-30—Filed

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