FIELD: organic chemistry. SUBSTANCE: products: derivatives of piperazinylalkyl of the formula where n is a whole number from 1 to 8; R hydrogen, halogen, C1-C4--alkyl, heteroaryl, sulfonyl, mono- or disubstituted sulfamide group, nitro, hydroxy, oxo, C1-C4--alkoxy, cyano, C1-C4-alkylcarboxy-group, nonsubstituted or substituted aryl, amino- or substituted amino-group. Reagent 1: where X halogen. Reagent 2: where R as indicated above. Reaction conditions: in the medium of organic solvent in the presence of base. Synthesized compounds were used in medicine. EFFECT: improved method of synthesis. 6 tbl
Authors
Dates
1995-08-27—Published
1991-10-15—Filed