PIPERAZINYLALKYL DERIVATIVES OR THEIR SALTS SHOWING INHIBITION OF ALCOHOL WITHDRAWAL SYNDROME Russian patent published in 1995 - IPC

Abstract RU 2042674 C1

FIELD: organic chemistry. SUBSTANCE: products: derivatives of piperazinylalkyl of the formula where n is a whole number from 1 to 8; R hydrogen, halogen, C1-C4--alkyl, heteroaryl, sulfonyl, mono- or disubstituted sulfamide group, nitro, hydroxy, oxo, C1-C4--alkoxy, cyano, C1-C4-alkylcarboxy-group, nonsubstituted or substituted aryl, amino- or substituted amino-group. Reagent 1: where X halogen. Reagent 2: where R as indicated above. Reaction conditions: in the medium of organic solvent in the presence of base. Synthesized compounds were used in medicine. EFFECT: improved method of synthesis. 6 tbl

Similar patents RU2042674C1

Title Year Author Number
DERIVATIVES OF ARYL- (OR HETEROARYL)-PIPERAZINYLALKYLAZOLES, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 1992
  • Ramon Merse Vidal'[Es]
  • Khordi Frigola Konstansa[Es]
  • Khuan Pares Korominas[Es]
RU2088582C1
DERIVATIVES OF 4-(2-PYRIMIDINYL)-1-PIPERAZINYL OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS 1991
  • Ogusto Kolombo Pinol'[Es]
  • Khordi Frigola Konstansa[Es]
  • Khuan Pares Korominas[Es]
RU2071474C1
METHOD OF SYNTHESIS OF DERIVATIVES OF ARYL- OR HETEROARYLPIPERAZINYLBUTYLAZOLE 1992
  • Ramon Merse Vidal'[Es]
  • Zhordi Frigalo Konstansa[Es]
  • Zhuan Pares Korominas[Es]
RU2053230C1
AGENT FOR COGNITIVE FUNCTION IMPROVEMENT 1992
  • Khordi Frigola-Konstansa[Es]
  • Khuan Pares-Korominas[Es]
RU2078568C1
METHOD OF SYNTHESIS OF 2-{4-[4-(4-CHLORO-1-PYRAZOLYL)BUTYL]-1-PIPERAZINYL}-PYRIMIDINE (LEZOPITRON) 1994
  • Ramon Merse-Vidal'
  • Khordi Frigola-Konstansa
RU2116305C1
BENZIMIDAZOLE DERIVATIVES, A METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF SHOWING ANTIHISTAMINIC ACTIVITY 1992
  • Marija Roza Kjuberes-Al'Tisent[Es]
  • Khordi Frigola Konstansa[Es]
  • Khuan Pares Korominas[Es]
RU2099336C1
DERIVATIVES OF 2-[4-(4-AZOLYLBUTYL)-1-PIPERAZINYL]-PYRIMIDINE OR THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 1994
  • Khordi Frigola Konstansa
  • Ramon Merse-Vidal'
RU2118318C1
BENZIMIDAZOLE DERIVATIVES SHOWING ANTIHISTAMINE ACTIVITY 1991
  • Marija Rosa Kuberes-Al'Tisent[Es]
  • Khordi Frigola-Konstansa[Es]
  • Khuan Pares-Korominas[Es]
RU2024519C1
DERIVATIVE OF THIENYLAZOLYLALKOXYETHANEAMINE, METHOD FOR ITS PREPARING (VARIANTS), PHARMACEUTICAL COMPOSITION, INTERMEDIATE COMPOUND AND METHOD FOR ITS PREPARING (VARIANTS) 1999
  • Merse-Vidal' Ramon
  • Andalus-Mataro Blas
  • Frigola-Konstansa Khordi
RU2213743C2
AGENT FOR TREATMENT OF NEUROGENIC INFLAMMATION 1999
  • Merse-Vidal' Ramon
  • Frigola-Konstansa Khordi
RU2212237C2

RU 2 042 674 C1

Authors

Khordi Frigola-Konstansa[Es]

Khuan Pares-Korominas[Es]

Dates

1995-08-27Published

1991-10-15Filed