FIELD: organic chemistry. SUBSTANCE: product: 2-propyl-3-(5-nitrofurfulydene)-amino-4(3H)-quinazoline of the formula (I) C16H14N4O4, empirical formula is , yield is 53% m. p. is 156-158 C. Reagent 1: 2-propyl-3-amino-4(3H)-quinazolone. Reagent 2: 5-nitrofurfurol. Conditions: heating in isopropanol medium in the presence of concentrated HCl. Synthesized compound is used in medicine. EFFECT: improved method of synthesis. 3 tbl
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Authors
Dates
1995-09-10—Published
1991-07-01—Filed