AZETIDINE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVING ANTIMICROBIAL ACTIVITY Russian patent published in 1995 - IPC

FIELD: substances having antimicrobial activity. SUBSTANCE: azetidine derivatives of the general formula 1 wherein A is a nitrogen atom, or CH or C-Ha; in which Hal is a chlorine or fluorine atom; R₁ is lower alkyl or cycloalkyl, lower halogenoalkyl or phenyl substituted by mono- or difluorine; R₂,R₃ and R₅ are the same or different and are hydrogen or lower alkyl; R₄ is hydroxyl, amino, aminoalkyl, alkylamino, dialkylamino, pyrrolyl-1 or pyrro lidinyl-1, alkylaminoalkyl, trifluoroacetamido; R₆ is hydrogen or amino, or A and R₁ together form and in that case have a chiral centre with the R or S consignation; R₇ is hydrogen or lower alkyl. EFFECT: improved properties of the title compounds. 1 tbl