FIELD: medicine. SUBSTANCE: this medicinal preparation is by 70 to 100 more effective than azathioprene (imuran) in capability of influencing process of formation of antibodies in spleen. Intraperitoneal four-shot administration of 30 mg/mg of azathioprene mass into highly responsive mice (after immunization with use of ram's erythrocytes) reduces (unproved data) AOK percentage by 24 Disclosed immunodepressant preparation, when administered in single dosage of 20 mk/kg concurrently with ram's erythrocytes, reduces AOK percentage by 74 in inductive phase and practically completely abrogates immune response in productive phase. EFFECT: broader range of applications of chemical compounds of series of nitrosopyridols. 2 tbl
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Authors
Dates
1995-10-10—Published
1989-07-14—Filed