PROCESS FOR PREPARING FABRIC-TYPE PLASMINOGENE ACTIVATOR, STRAIN OF CULTIVATED ANIMAL CELLS, FABRIC-TYPE PLASMINOGENE ACTIVATOR CHO PRODUCER Russian patent published in 1995 - IPC

Abstract RU 2046827 C1

FIELD: genetic engineering. SUBSTANCE: the process for preparing a fabric-type plasminogene activator comprises cultivating strain CHO K1 ATCC NCCL61 transformed by recombinant plasmid DNA pETPFR, growing transformants in the presence of a competing activity inhibitor DHFR at a concentration of 20 to 500.000 nm, isolating and purifying the desired product. EFFECT: more efficient preparation process. 3 cl, 3 tbl

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RU 2 046 827 C1

Authors

David Vannorman Geddel'[Us]

Vil'Jam Dzhehk Kor[Us]

Diane Pennika[Us]

Gordon Allen Vekhar[Us]

Dates

1995-10-27Published

1987-06-05Filed