FIELD: biotechnology, immunology. SUBSTANCE: method involves immunization of rat (strain Wistar) with homologous antigen of mite encephalitis virus - rat brain suspension at virus activity 9.5 lg LD 50/ml, not less, by conventional schemes. The latter consists of 3-5 injections at obligatory interval for 1.5-2 months between the first and the second one that can be shortened to 2-3 weeks between the following antigen administration. Ascitic fluid accumulation is induced by rat ovary tumor cells inoculation. Immunoglobulin is isolated with polyethylene glycol. EFFECT: improved method of antibody preparing.
| Title | Year | Author | Number |
|---|---|---|---|
| STRAIN OF VERNAL ENCEPHALITIS (TICK-BORNE ENCEPHALITIS) FAMILIES FLAVIVIRIDAE, SORTS FLAVIVIRUS VIRUS, USED FOR PREPARATION OF DIAGNOSTIC PREPARATIONS | 2007 |
|
RU2352632C2 |
| SET FOR DIFFERENTIAL DIAGNOSIS OF OMSK HEMORRHAGIC FEVER AND TICK-BORNE ENCEPHALITIS | 1993 |
|
RU2061959C1 |
| ALMA-ARASON NO. KAZ-1380 KL VIRUS STRAIN USED FOR PRODUCING DIAGNOSTIC PREPARATIONS | 0 |
|
SU1182077A1 |
| METHOD FOR PRODUCING A STANDARD SAMPLE OF HUMAN IGG ANTIBODY CONTENT TO TICK-BORNE ENCEPHALITIS VIRUS | 2020 |
|
RU2735782C1 |
| METHOD OF PREPARING OF INDUSTRIAL STRAINS OF TICK-BORNE ENCEPHALITIS VIRUS | 0 |
|
SU1818343A1 |
| STRAIN OF VIRUS OF VERNAL ENCEPHALITIS FOR MAKING DIAGNOSTIC PREPARATIONS | 0 |
|
SU1634711A1 |
| STRAIN OF HYBRID CULTURED CELLS MUS MUSCULUS - A PRODUCER OF MONOCLONAL ANTI- BODIES USED FOR VIRAL HEMORRHAGIC RABBIT DISEASE DIAGNOSIS | 1992 |
|
RU2007452C1 |
| METHOD OF PREPARING ANTIBODIES RAISED TO ARBOVIRUSES OF CALIFORNIUM AND BATAI ENCEPHALITIS COMPLEX | 1992 |
|
RU2111013C1 |
| STRAIN OF VIRUS GISSAR FOR MAKING DIAGNOSTIC PREPARATIONS | 0 |
|
SU1708837A1 |
| STRAIN OF VIRUS OF TICK-BORNE ENCEPHALITIS NO 139 FOR PREPARATION OF HEMAGGLUTINATING INACTIVATED DIAGNOSTICUM | 0 |
|
SU1071634A1 |
