FIELD: pharmaceutical industry. SUBSTANCE: method involves the preparing the stable iron-sorbitol complex - hexahydric alcohol with trivalent iron that is stable at storage. Reaction mixture consisting of sorbitol, dextrin, citric acid and water is heated to 70 C and sodium hydroxide and ferric chloride were added to reaction medium by drops at thorough stirring. Complex is synthesized at pH = 9.0-9.5 and bubbling is carried out with gaseous nitrogen or compressed sterile air. EFFECT: improved method of drug making. 4 cl
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Authors
Dates
1997-05-10—Published
1994-07-05—Filed