6-OXO-AZEPINOINDOLE COMPOUNDS AND THEIR PHYSIOLOGICALLY TOLERANTABLE ACID SALTS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHODS OF THEIR SYNTHESIS Russian patent published in 1997 - IPC

FIELD: organic chemistry. SUBSTANCE: product: derivative of 3,4,5,6-tetrahydro-6-oxo-1H-azepino-[5,4,3-cd]-indole of the formula where: R¹ - H, lower alkyl or phenyl-lower alkyl group that can be mono- or disubstituted with lower alkoxy or lower alkyl at phenyl ring; R² - H or lower alkyl; R³ - H or halogen; n = 1 or 2 if -(CH₂)_n-chain is located in ring position; R⁴ - H, C_1-5-alkyl, C_3-6-cycloalkyl, C₄-cycloalkyl, phenyl-lower alkyl group; R⁵ - H, C_1-5-alkyl or phenyl-lower alkyl group; D - bond or -N=CH-group, and their physiologically acceptable salts, methods of their synthesis and pharmaceutical compositions containing their as the main component. Synthesized compounds were used in medicine since they regulate stomach motor activity and show serotonine-agonistic action and can be used against migraine. EFFECT: improved method of synthesis. 14 cl