METHOD FOR PRODUCTION OF LACTONE 1R, CIS-2,2-DIMETHYL-3-FORMYLCYCLOPROANE-1-CARBOXYLIC ACID AND HALEGENATED DERIVATIVES OF 6,6-DIMETHYL-3-OXABICYCLO-[3 Russian patent published in 1997 - IPC

Abstract RU 2086546 C1

1.0]-HEXANONE-2. FIELD: organic synthesis, synthesis of lactone 1R, cis-2,2-dimethyl-3-formylcyclopropane-1-carboxylic acid. SUBSTANCE: halogen derivative of 6,6-dimethyl-3-oxabicyclo-[3.1.0] -hexanone having formula where A is CHX3,CX2H or CZ3, X is Cl, Br, J. Compound II having formula is used as reagent 1, halogen being used as reagent 2. Compound II is affected by treatment with halogen to prepare compound III (if it is necessary to prepare compound III halogenation is carried out) where A is CH3. The process is followed by treatment with basic agent to prepare compound IV having formula . To prepare acid if it is necessary acidifying takes place, the process is followed by oxidation thus obtained salt or acid to prepare compound having formula I. EFFECT: improved efficiency. 15 cl

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RU 2 086 546 C1

Authors

Neerzha Batnagar[In]

Fransi Brion[Fr]

Kolett Kolladan[Fr]

Dates

1997-08-10Published

1992-10-08Filed