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2 093 525

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C1

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IPC

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Application

95117737/04, 1995-10-18

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Actual filing date

1995-10-18

(45)

Published

1997-10-20

(72)

Inventor

Tolstikov G.A.Monakov Ju.B.Baschenko I.A.Jusupova F.G.Garipova M.I.Mannanova G.V.Karaush N.V.Zarudij F.S.Popova I.Ju.

(73)

Holder

Institut Organicheskoj Khimii Ufimskogo Nauchnogo Tsentra Ran

CROSS-LINKED POLYVINYL ALCOHOL WITH THE IMMOBILIZED META-AMINOPHENYLBORONIC ACID AS A SORBENT FOR GLYCOSYLATED HEMOGLOBIN ASSAY BY AFFINITY METHOD Russian patent published in 1997 - IPC

Abstract RU 2093525 C1

FIELD: analytical biochemistry, polymers. SUBSTANCE: invention proposes new sorbent for affinity assay of the glycosylated hemoglobin. High effectiveness of sorbent by ligand (above 20-fold use of 1 ml sorbent) is provided by the presence of cross-linked polyvinyl alcohol with the immobilized m-aminophenylboronic acid of the general formula given in description where amount of m-aminophenylboronic acid in sorbent is 0.37-1.49%, molecular mass of an active chain of cross-linked polyvinyl alcohol is 2·I03÷3·I03, Da, swelling coefficient is 80-100%. Sorbent can be used in medicine for diagnosis and course severity of diabetus mellitus. EFFECT: improved quality and property of sorbent. 3 tbl

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RU 2 093 525 C1

Authors

Tolstikov G.A.

Monakov Ju.B.

Baschenko I.A.

Jusupova F.G.

Garipova M.I.

Mannanova G.V.

Karaush N.V.

Zarudij F.S.

Popova I.Ju.

Dates

1997-10-20—Published

1995-10-18—Filed

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