FIELD: medicine, dermatology. SUBSTANCE: method involves the cutaneous use of antibiotic tarvid as its liposomal form. Liposomes were prepared on the base of marine mammalian subcutaneous fat liquid glycerides in the presence of phosphate buffer, pH = 6.7-6.9, by mechanical dispersing and ultrasonic oscillation treatment for 20-40 s. Dimethylsulfoxide is used as a transport agent in liposomal form. EFFECT: enhanced bioavailability of antibiotic, decreased cost of treatment. 3 tbl, 1 dwg
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Authors
Dates
1997-12-10—Published
1991-12-27—Filed