FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to medicine, namely to methods for producing wound healing drugs for external application. Producing a liposomal agent exhibiting wound healing action requires phospholipid extraction from Baikal seal liver; prepared mixed phospholipids and Baikal seal fat are dissolved in an organic solvent in the ratio 4:6 with the antioxidant α-tocopherol added. A thin layer of lipids is dried in a rotary evaporator; a buffer solution is added; the mixture is agitated to prepared a homogeneous suspension. It is followed with ultrasound preparation of the lipid mixture with water cooling. The liposomal suspension mixed in the ratio 1:1 with pre-melted mixed polyethylene glycols 1000 and 6000 Da taken in the ratio 9:1. Further, the produced mixture is homogenised to a homogeneous mass.
EFFECT: use of the method allows producing the liposomal agent for external application exhibiting wound healing action.
3 tbl, 3 dwg, 3 ex
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Authors
Dates
2011-04-27—Published
2009-11-30—Filed