FIELD: medicine. SUBSTANCE: method involves taking blood samples in early pregnancy period or before pregnancy. Blood serum is produced, ELI-P test system (cleaned antigens) is obtained and enzyme immunoassay (solid phase) is carried out to determine immune reactivity of serum auto-antibodies of female organism exerting essential influence upon normal embryo/fetogenesis and directed to antigens participating in processes of fetal tissues and organs development, for instance to protein S 100 as basic myelin protein, stable anion-binding protein of chromatin ABX 14-18, membrane protein MP65. Data on tested sera immune reactivity deviation from normal values level to any of them being obtained, fetus development disorder risk level is determined from the marked deviation degree. EFFECT: availability for mass-scale examination. 9 tbl
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Authors
Dates
1998-03-27—Published
1995-04-14—Filed