HETEROCYCLIC AMINES, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 1998 - IPC

FIELD: organic chemistry. SUBSTANCE: product: heterocyclic amines of the general formula (I): where X means CH₂-group or -S-group; B means groups -CO-, -CH₂--OCO-, -CH₂--OCS-, -CH₂--NHCO- and -CH₂--NHCS-; D means benzhydryl or phenyl groups optionally substituted with halogen atoms and heterocyclic group and others; Y means simple carbon-carbon bond or group of the formula -CH₂-CH₂- and others; A is taken from the group involving carboxyl group, amide, sulfoneamide or hydroxyamide and others. Reagent 1: compound of the formula (II) . Reagent 2: compound of the formula (III) . Invention proposes compound of the formula (Ia) where A′ - halogen atom and pharmaceutical composition showing antiasthmatic activity and antiinflammatory effect on respiratory way that can be used in medicine. EFFECT: improved method of synthesis, enhanced effectiveness of treatment. 9 cl