PREPARATION "LOCFERON" FOR TREATMENT AND PROPHYLAXIS OF VIRAL DISEASES AND A METHOD OF ITS PREPARING Russian patent published in 1998 - IPC

Abstract RU 2108804 C1

FIELD: biotechnology, medicine. SUBSTANCE: invention relates to curative-prophylaxis preparation based on human leukocyte interferon. Preparation "Locferon" has interferon synthesized by donor blood leukocytes induced by virus strain-inducer of virus parainfluenza-1 Sendai GKV N 2339. Preparation is concentrated and purified by ultrafiltration. Preparation has 8000 IU antiviral activity in one ampoule - interferon, cellular mediators of molecular mass 10-100 kDa, ovalbumin - less 1 ng/ml, sodium chloride and stabilizing agent. "Locferon" inhibits multiplication of broad spectrum viruses - herpes viruses, adenoviruses, enteroviruses and others. Preparation blocks intracellular replication of viral particles and activates protective cellular response reactions. EFFECT: enhanced effectiveness of preparation. 3 cl

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RU 2 108 804 C1

Authors

Jakushevich Ju.E.

Ilidzhev A.K.

Udotov Ju.M.

Popov V.F.

Naumova N.N.

Dates

1998-04-20Published

1997-06-24Filed