FIELD: biotechnology, medicine. SUBSTANCE: invention relates to curative-prophylaxis preparation based on human leukocyte interferon. Preparation "Locferon" has interferon synthesized by donor blood leukocytes induced by virus strain-inducer of virus parainfluenza-1 Sendai GKV N 2339. Preparation is concentrated and purified by ultrafiltration. Preparation has 8000 IU antiviral activity in one ampoule - interferon, cellular mediators of molecular mass 10-100 kDa, ovalbumin - less 1 ng/ml, sodium chloride and stabilizing agent. "Locferon" inhibits multiplication of broad spectrum viruses - herpes viruses, adenoviruses, enteroviruses and others. Preparation blocks intracellular replication of viral particles and activates protective cellular response reactions. EFFECT: enhanced effectiveness of preparation. 3 cl
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Authors
Dates
1998-04-20—Published
1997-06-24—Filed