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Application

96111361/13, 1996-06-05

(22)

Actual filing date

1996-06-05

(45)

Published

1998-06-20

(72)

Inventor

Gashimova D.T.Gabidullin Z.G.Mavzjutov A.R.Bulgakov A.K.Sufijarova R.Z.

(73)

Holder

Bashkirskij Gosudarstvennyj Meditsinskij Universitet

STRAIN OF BACTERIUM MORGANELLA MORGANII - A PRODUCER OF THERMOLABILE ENTEROTOXIN Russian patent published in 1998 - IPC

Abstract RU 2113473 C1

FIELD: biotechnology. SUBSTANCE: Strain M. morganii N 4102 is isolated from sick child with enteric infection and deposited in Collection of The State Scientific-Research Institute of standardization and control of medicinal and biological preparations at number 242. Conditions of culture storage: after lyophilic drying or culture grown on 0.3% plain agar (pH 7.2-7.4) poured with sterile Vaseline oil at 4 C. Multiplication media: Hottinger broth (pH 7.2-7.4) containing 5% rabbit erythrocytes for 20 h. Genetic features of the strain: Hly+, Ent+:penR, Hag(MS+/MR+). Strain shows resistance to penicillin, ampicillin, erythromycin, methicillin, lyncomycin, tetracycline, gentamycin, streptomycin. Invention can be used for production of thermolabile enterotoxin and anatoxin from M. morganii at vaccines production. EFFECT: strain indicated above. 1 tbl

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RU 2 113 473 C1

Authors

Gashimova D.T.

Gabidullin Z.G.

Mavzjutov A.R.

Bulgakov A.K.

Sufijarova R.Z.

Dates

1998-06-20—Published

1996-06-05—Filed

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