FIELD: organic chemistry and chemical technology. SUBSTANCE: products: derivatives of carbazolone of the formula (I) where A is group of the formula CH2R; R is -OH or 2-methyl-1H- -imidazole-1-yl; B is group ; R1 is H, CH3,C2H5 or A and B form together group of the formula (VII) ; R2 is CH3,C2H5 or A and B form together group of the formula (VIII) . Compound of the formula (I) is used as an intermediate substance for synthesis of ondansetrone that is an antiemetic agent. EFFECT: increased yield and purity degree of ondansetrone. 3 cl, 11 ex
Title | Year | Author | Number |
---|---|---|---|
DERIVATIVES OF ANDROSTANE SUBSTITUTED AT 16-POSITION WITH QUATERNARY AMMONIUM GROUP, PHARMACEUTICAL COMPOSITION | 1993 |
|
RU2124021C1 |
METHOD FOR PREPARING β-SUBSTITUTED 4-AZAANDROSTENE | 1993 |
|
RU2109746C1 |
17-HALOGEN-4-AZAANDROSTENE DERIVATIVES AND METHOD OF PREPARATION THEREOF | 1993 |
|
RU2103275C1 |
DERIVATIVES OF PROPANE-2-OL | 1994 |
|
RU2127277C1 |
PEPTIDE DERIVATIVES OR ACID ADDITION SALTS THEREOF AND PHARMACEUTICAL COMPOSITION | 1991 |
|
RU2037499C1 |
PENTAPEPTIDE AND PHARMACEUTICAL COMPOSITION CONTAINS INHIBITOR OF PROLIFERATION OF EPIDERMAL CELLS | 1991 |
|
RU2018510C1 |
DIKETONEIMINE DERIVATIVE AS AN INTERMEDIATE PRODUCT FOR SYNTHESIS OF RANITIDINE AND METHOD OF ITS SYNTHESIS | 1991 |
|
RU2042671C1 |
PROCESS FOR PRODUCING RACEMICALY OR OPTICALLY ACTIVE 4-SUBSTITUTED 1,3,4,5-TETRAHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE | 0 |
|
SU942594A3 |
METHOD OF PREPARING 1,2,3,9-TETRAHYDRO-9-METHYL-3-(2- METHYL-1H-IMIDAZOL-1-YL)-METHYL-4H-CARBAZOL-4-ONE OF FORMULA I | 1993 |
|
RU2109741C1 |
METHOD FOR PREPARING IMIDAZOLYL COMPOUNDS | 2003 |
|
RU2314296C2 |
Authors
Dates
1998-10-10—Published
1993-10-13—Filed