TRIAZOLOPYRIMIDINE DERIVATIVES, A METHOD OF THEIR SYNTHESIS, A FUNGICIDE COMPOSITION, A METHOD OF STRUGGLE AGAINST FUNGI Russian patent published in 1999 - IPC

FIELD: organic chemistry, fungicides. SUBSTANCE: invention relates to derivatives of triazolopyrimidine of the general formula (I) where R¹ is possibly substituted alkyl, cycloalkyl or bicycloalkyl; R² is hydrogen atom; R³ is a 3-4-membered heterocycle containing one S-atom; R⁴ is halogen atom. Compounds are synthesized by interaction of a compound of the formula (II) where Hal - chlorine or bromine with a compound of the formula HN-R¹R² and a compound of the formula (I) is synthesized where R⁴ - chlorine or bromine atom followed by optionally reaction of the obtained compound (I) with fluorinated agent and producing a compound (I) where R⁴ is fluorine atom. Compounds of the formula (I) exhibit activity against fungi of class ascomycetes, for example, Venturia inaequalis, Botrytis cinerea and Alternaria solani. EFFECT: improved method of synthesis, enhanced effectiveness of compounds. 11 cl, 2 tbl, 12 ex