FIELD: chemical industry. SUBSTANCE: novel n-butyl- amide-2-anilino-6,7-dihydro-5H-pyrindine-3-carboxylic acid of formula I: 
. Compound is prepared by reacting n-butylamine 2-chloro-6,7-dihydro-5H-pyrindine-5- carboxylic acid with aniline hydrochloride in butanol C19H23N3O, mp 132-134 C. Compound (I) has antiinflammatory activity. Antiinflammatory activity of compound (I) in 50 ml/kg is by 1.4 times higher than that of orthophene. ZD50 is more than 500 mg/kg. EFFECT: improved properties of the title compound. 2 ex, 1 tbl
| Title |
Year |
Author |
Number |
| 2-OXO-1,2,5,6,7,8-HEXAHYDROQUINOLINE-4-CARBOXYLIC ACID ANILIDE SHOWING ANTI-INFLAMMATORY AND ANALGETIC ACTIVITY |
1999 |
- Smirnova T.A.
- Gavrilov M.Ju.
- Vasiljuk M.V.
- Zaks A.S.
- Kon'Shin M.E.
|
RU2154061C1 |
| 2-(4-CHLOROANILINO)-CINCHONNIC ACID ISOPROPYLAMIDE SHOWING AN ANTI-INFLAMMATORY AND ANALGETIC ACTIVITY |
1997 |
- Mikhalev A.I.
- Kon'Shin M.E.
- Zaks A.S.
- Zueva M.V.
- Vakhrin M.I.
|
RU2130018C1 |
| N-(3'-CHLOROBUTENE-2'-YL)-ANTHRANILIC ACID ANILIDE ELICITING ANTI-INFLAMMATORY AND ANALGETIC ACTIVITY |
2000 |
- Podchezertseva A.V.
- Korkodinova L.M.
- Vasil'Eva M.Ju.
- Mardanova L.G.
- Kolla V.Eh.
|
RU2180657C1 |
| N-ALLYLANTHRANILIC ACID AMIDE ELICITING ANTI-INFLAMMATORY, ANALGETIC AND ANTIHYPOXIC ACTIVITY |
2000 |
- Shakirova A.B.
- Korkodinova L.M.
- Vasil'Eva M.Ju.
- Mardanova L.G.
- Kolla V.Eh.
|
RU2180656C1 |
| N-(4-CHLOROBENZOYL)-5-BROMOANTHRANYL ACID AMID EXHIBITING ANTI-INFLAMMATORY AND ANALGETIC ACTIVITIES |
2003 |
- Dolzhenko A.V.
- Korkodinova L.M.
- Kotegov V.P.
- Vasiljuk M.V.
|
RU2247717C2 |
| N-(3'-CHLOROBUTENE-2'-YL)ANTHRANILIC ACID ACIARYLAMIDES ELICITING ANTI-INFLAMMATORY ACTIVITY |
2000 |
- Podchezertseva A.V.
- Korkodinova L.M.
- Shakirova A.B.
- Vasil'Eva M.Ju.
- Mardanova L.G.
- Kolla V.Eh.
|
RU2181718C2 |
| ANTI-INFLAMMATORY ACTIVITY |
1999 |
- Korkodinova L.M.
- Vasil'Eva M.Ju.
- Mardanova L.G.
- Shakirova A.B.
- Vakhrin M.I.
- Feshin V.P.
- Kolla V.Eh.
|
RU2170726C1 |
| 1-PHENYL-2-[BETA-(5'-NITRO-2'-FURYL)VINYL]-6,7,8,9-TETRAHYDROPYRIMIDO[4,5- B]QUINOLIN-4-ON AND 1-M-CHLOROPHENYL-2-[BETA-(5'-NITRO-2'-FURYL)VINYL]-7,8- DIHYDRO-6H-PYRIMIDO[4,5-B]PYRIMIDIN-4-ON WITH ANTIMICROBIAL ACTIVITY |
1999 |
- Galeeva R.N.
- Gavrilov M.Ju.
- Voronina Eh.V.
- Rudometova E.V.
- Kon'Shin M.E.
|
RU2165421C2 |
| N-(3'-CHLOROBUTENE-2'-YL)-ANTHRANILIC ACID AMIDE SHOWING ANTI-INFLAMMATORY ACTIVITY |
2000 |
- Shakirova A.B.
- Korkodinova L.M.
- Podchezertseva A.V.
- Vasil'Eva M.Ju.
- Mardanova L.G.
- Kolla V.Eh.
|
RU2189377C2 |
| 9-BENZYLIDENEHYDRAZINO-1,2,3,4-TETRAHYDROACRIDINE SHOWING ANALGETIC AND ANTIBACTERIAL ACTIVITY AGAINST STAPHYLOCOCCUS AUREUS |
1999 |
- Dontsova L.P.
- Konshin M.E.
- Kolla V.Eh.
- Mardanova L.G.
- Novoselova G.N.
|
RU2161606C2 |
