FIELD: medicine, experimental oncology. SUBSTANCE: invention proposes to use a physiological solution obtained by bubbling with ozone-oxygen mixture at the rate of gas flow 0.5-1 l/min for 15-20 min at ozone concentration in gaseous mixture 800-5 000 mcg/l. Solution is administrated into tumor directly by perimeter of its localization at volume 0.5-1.5 ml. Invention can be used for validity of the following study and using the ozonotherapy for treatment of patients with malignant neoplasms. EFFECT: broadened arsenal of treatment methods. 5 tbl, 3 ex
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