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2 139 731

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C1

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IPC

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Application

95112506/14, 1993-11-12

(24)

Start date

1993-11-12

(22)

Actual filing date

1993-11-12

(45)

Published

1999-10-20

(72)

Inventor

Darrel R.AndersonVil'Jam Kh.RastetterNehbil KhannaDzhon E.LeonardRoland A.N'JumehnMitchell E.Reff

(73)

Holder

Ajdek Farmas'Jutikals Korporejshn

METHODS OF TREATMENT, ANTIBODIES, HYBRIDOMA Russian patent published in 1999 - IPC

Abstract RU 2139731 C1

FIELD: mdicine, oncology, immunology. SUBSTANCE: invention relates to the treatment of patients with B-cellular lymphoma. Invention proposes a new immunologically active chimeric antibody - anti-C20 among them an antibody labeled with radioisotope and also a hybridoma producing an antibody showing specificity with respect to C20-antigen. Method of treatment involves the administration of indicated antibody preparations by three stages using different therapeutically effective amounts of these antibodies. EFFECT: enhanced specificity of effect on malignant cells. 15 cl, 3 tbl

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RU 2 139 731 C1

Authors

Darrel R.Anderson

Vil'Jam Kh.Rastetter

Nehbil Khanna

Dzhon E.Leonard

Roland A.N'Jumehn

Mitchell E.Reff

Dates

1999-10-20—Published

1993-11-12—Filed

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