FIELD: medicine, immunology.
SUBSTANCE: claimed method includes administration of composition comprising immunoregulatory anti-CD80 antibody or immunoregulatory binding fragment thereof and anti-CD80 antibody having activity directed to attenuation of B-cells in claimed dosages and regimes. Method of present invention makes it possible to effectively treat of autoimmune diseases due to attenuation of B-cell population caused by selective directivity of claimed combination against both activated and non-activated B-cells.
EFFECT: effective method for treatment of autoimmune diseases.
3 ex, 1 tbl, 36 cl
| Title |
Year |
Author |
Number |
| APPLICATION OF ANTI-CD40-ANTIBODIES |
2006 |
- Aukerman Sharon Lea
- Lukman Mokhammad
|
RU2442606C2 |
| TREATMENT OF B-CELLULAR MALIGNANT TUMORS USING ANTI-CD40L ANTIBODIES IN COMBINATION WITH ANTI-CD20 ANTIBODIES AND/OR BY CHEMOTHERAPY AND RADIOTHERAPY |
2000 |
- Khanna Nabil
- Kharikharan Kandasami
|
RU2305561C2 |
| IMMUNOTHERAPY OF MALIGNANT DISEASES OF B-CELLS AND AUTOIMMUNE DISEASES WITH APPLICATION OF CONJUGATE AND NONCONJUGATE ANTIBODIES, COMBINATIONS OF ANTIBODIES AND CONJOINT PROTEINS |
2003 |
- Goldenberg Dehvid M.
- Khansen Khans
|
RU2335297C2 |
| APPLICATION OF SINGLE DOSE OF CD20-SPECIFIC BINDING MOLECULES |
2006 |
|
RU2421242C2 |
| METHOD AND COMPOSITION FOR REDUCTION OF MICROMOLECULE AGGREGATION UNDER PHYSIOLOGICAL CONDITIONS |
2009 |
- Lobo Brajan
- Lo Sabrina
- Vang Juchang Dzhon
- Vong Rita
|
RU2563823C2 |
| MONOCLONAL ANTI-CD20-ANTIBODY |
2006 |
- Numadzaki Masanori
- Nakamura Tehtsuo
- Usuda Sadakadzu
- Padlan Ehduardo A.
|
RU2415871C2 |
| ANALYSIS OF NEUTRALISING ANTIBODIES AND ITS APPLICATION |
2004 |
|
RU2370775C2 |
| BISPECIFIC ANTIBODIES TO HUMAN CD20/HUMAN TRANSFERRIN RECEPTOR AND METHODS FOR THEIR USE |
2016 |
- Dyurr, Kharald
- Fenn, Sebastyan
- Gepfert, Ulrikh
- Imkhof-Yung, Zabine
- Klyajn, Kristian
- Lariver, Loran
- Molkhoj, Mikhel
- Regula, Jerg Tomas
- Ryuger, Petra
- Shefer, Volfgang
|
RU2753390C1 |
| DECREASING B-CELL COUNT WITH USING CD37-SPECIFIC AND CD20-SPECIFIC BINDING MOLECULES |
2006 |
- Grosmehjr Laura S'Ju
- Khajdehn-Ledbehttehr Marta S'Juzan
- Ledbehttehr Dzheffri A.
- Tompson Piter Armstrong
- Sajmon Sandi Aleksander
- Brehdi Uill'Jam
|
RU2423381C2 |
| USING ANTIBODIES FOR TREATING AUTOIMMUNE DISEASES IN PATIENT WITH INADEQUATE RESPONSE TO TNF-ALPHA INHIBITOR |
2008 |
|
RU2489166C2 |
