METHOD OF PREPARING MORPHOLINIUM 3-METHYL-1,2,4-TRIAZOLYL-5-THIOACETATE EXHIBITING HEPATO-PROTECTIVE, WOUND-HEALING, AND ANTIVIRAL ACTIVITIES Russian patent published in 2000 - IPC

Abstract RU 2144534 C1

FIELD: synthesis of biologically-active compounds. SUBSTANCE: method involves mixing 3-methyl-1,2,4-triazolin-5-thione with morpholine, heating reaction mixture in organic solvent, and isolation of desired product in the form of crystalline powder. In addition, alkali metal chloroacetate is also added to reaction mixture at molar ratio to morpholine 1:(1.0-1.1). EFFECT: increased purity, activity, and yield of product. 1 tbl, 6 ex

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RU 2 144 534 C1

Authors

Knysh Evgenij Grigor'Evich

Trubchanin Nikolaj Ivanovich

Dates

2000-01-20Published

1997-06-30Filed