FIELD: organic chemistry or heterocyclic compounds, chemical technology.
SUBSTANCE: invention relates to technology for manufacturing heterocyclic compounds, in particular, to technology for manufacturing 3-methyl-1,2,4-triazolyl-5-thioacetate morpholinium that is known as a substance for pharmaceutical designation "thiotriazoline". Invention describes a method for preparing 3-methyl-1,2,4-triazolyl-5-thioacetate morpholinium that involves reaction of 3-methyl-1,2,4-triazolyl-5-thioacetic acid with morpholine in liquid medium wherein methylene chloride is used as a liquid medium. Method provides significant elevating the yield percent of the end product, enhances its quality and significant reducing industrial consumptions.
EFFECT: improved preparing method.
4 cl, 1 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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| METHOD OF SYNTHESIS OF ARYLTRIAZOLINE | 1990 |
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SU1738089A3 |
