FIELD: medicine, pharmacy. SUBSTANCE: pharmaceutical composition has antibody raised to interkeukin-6 receptors and can be used for preparing preparations for treatment of patients with diseases caused by blood state damage, immunological disturbances, tumors and other diseases caused by formation of IL-6. In part, composition can be used for prophylaxis and treatment of patients with plasmacytosis, hyperimmunoglobulinemia, anemia, nephritis, cachexia, rheumatism, Kastlman's disease, mesangial proliferating nephritis. Monoclonal antibody, antibody PM-1, chimeric antibody, human antibody, modified human antibody PM-1 can be used as an antibody. Composition shows effectiveness against multitude of diseases caused by formation of IL-6 but it does not shows any effect at normal level of IL-6. EFFECT: enhanced effectiveness of composition. 14 cl, 18 dwg, 4 tbl, 3 ex
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Authors
Dates
2000-04-20—Published
1995-10-20—Filed