DRUGS AGAINST CHRONIC RHEUMATIC ARTHRITIS CONTAINING ANTAGONIST OF IL-6 AS EFFECTIVE COMPONENT Russian patent published in 2000 - IPC

Abstract RU 2147443 C1

FIELD: medicine, pharmacy. SUBSTANCE: invention relates to pharmaceutical composition used for treatment of patients with chronic rheumatic arthritis and to inhibitor of synovial cells proliferation. Composition has an antibody against interleukin-6 receptor as an effective component and an inhibitor has an antagonist of interleukin-6 taken among the group including interleukin-6 antibody, interleukin-6 receptor antibody, antibody gp130, modified interleukin-6, antisense interleukin-6 receptor, noncomplete interleukin-6 peptide and noncomplete interleukin-6 receptor peptide. Invention provides inhibition of anomal proliferation of synovial cells in patients with rheumatic arthritis. EFFECT: enhanced effectiveness of drugs. 6 cl, 1 tbl, 6 dwg, 6 ex

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RU 2 147 443 C1

Authors

Tadamitsu Kisimoto

Masakhiko Mikhara

Joitiro Morija

Josijuki Okhsugi

Dates

2000-04-20Published

1995-06-07Filed