METHOD OF HUMAN ANTIDIPHTHERITIC IMMUNOGLOBULIN PREPARING Russian patent published in 2000 - IPC

Abstract RU 2150960 C1

FIELD: medicine, immunology. SUBSTANCE: invention relates to methods of preparing curative preparations from immunized donor blood, in part, to methods of preparing human antidiphtheritic imuunoglobulin for intravenous administration. In 30 days after immunization with diphtheritic anatoxin blood is taken off in donors. Blood plasma with titer value of antidiphtheritic antibodies 1:160 and above is taken off and boiler mixture containing antidiphtheritic antibodies 1: 1280, not less, is formed. Then blood plasma is fractionated by alcohol method at low temperatures. The end product is obtained as solution of human antidiphtheritic immunoglobulin. Obtained preparation is homologous one, it shows high specificity and effectiveness in treatment of patients with diphtheria, especially in treatment of patients with enhanced sensitivity to heterologous protein and does not cause allergic complications. EFFECT: improved method of preparing, valuable properties. 1 tbl, 1 ex

Similar patents RU2150960C1

Title Year Author Number
METHOD OF PREPARING IMMUNOGLOBULIN PREPARATION FOR DIPHTHERIA PROPHYLAXIS AND THERAPY 1994
  • Aleshkin V.A.
  • Borisova I.V.
  • Sokolov A.L.
RU2074725C1
PREPARATION FOR PROPHYLAXIS AND TREATMENT OF DIPHTHERIA AND METHOD OF ITS PREPARING 1999
  • Nikolaeva A.M.
  • Vedernikova N.V.
  • Efimova N.P.
RU2174408C2
METHOD TO TREAT DIPHTHERIA 1994
  • Feklisova L.V.
  • Shebekova V.M.
  • Shchipkova L.G.
  • Shkuratova O.V.
RU2106144C1
METHOD OF VACCINATION AGAINST DIPHTHERIA IN CHILDREN WITH SYSTEM CONJUNCTIVE TISSUE DISEASES 1996
  • Koshcheeva Ju.V.
  • Kharit S.M.
RU2127601C1
METHOD OF PREPARING ANTIBODIES FOR MITE ENCEPHALITIS VIRUS DIAGNOSTIC PREPARATION PRODUCTION 1993
  • Podoplekina L.E.
  • Sharova O.I.
  • Unger G.N.
RU2063245C1
METHOD OF PREPARING HUMAN ANTISTAPHYLOCOCCUS IMMUNOGLOBULIN FOR INTRAVENOUS ADMINISTRATION 1996
  • Sharygin S.L.
  • Sapozhnikova V.S.
  • Mal'Tseva O.V.
  • Starostina E.E.
  • Anastasiev V.V.
RU2141341C1
METHOD OF IMMUNOGLOBULIN PREPARING FOR INTRAVENOUS ADMINISTRATION SHOWING DECREASED ANTICOMPLEMENTARY ACTIVITY 1989
  • Kuz'Michev V.A.
  • Sarafanova L.N.
  • Krokhina M.A.
  • Gusenova F.M.
  • Pozina I.M.
  • Migunov V.N.
  • Rusanov V.M.
RU1693751C
METHOD OF PURIFICATION OF HUMAN IMMUNOGLOBULIN ANTITETANUS PREPARATION 1988
  • Sapozhnikova V.S.
  • Dumkin I.M.
SU1628293A1
METHOD OF PREPARING ERYTHROCYTE IMMUNODIAGNOSTICUM AND METHOD OF EVALUATION OF BODY IMMUNORESISTANCE 1996
  • Leshchuk S.I.
  • Popkova S.M.
  • Shmeleva E.A.
RU2142807C1
SECRETORY IMMUNOGLOBULIN A PREPARATION POSSESSING ANTIVIRAL OR ANTIBACTERIAL EFFECT 2003
  • Kovshik I.G.
  • Lozhkin I.D.
RU2264229C2

RU 2 150 960 C1

Authors

Shchipkova L.G.

Shkuratova O.V.

Nikitina L.N.

Anastasiev V.V.

Feklisova L.V.

Shebekova V.M.

Kajrova N.I.

Dates

2000-06-20Published

1995-07-18Filed