METHOD OF PREPARING MEDICINAL FORM OF ISONIAZIDE SHOWING DECREASED HEPATOTOXICITY Russian patent published in 2000 - IPC

Abstract RU 2153878 C1

FIELD: pharmaceutical industry. SUBSTANCE: isoniazide is mixed with beet pectin and sucrose in the ratio 1:6:1. 40-% ethyl alcohol is added to total mixture amount in parts as a moistening agent up to formation of mass to be granulated. Obtained granules are treated with 10% solution of calcium chloride and dried at 60 ± 5 C for 1 h. EFFECT: decreased hepatotoxicity, retained tuberculostatic activity of agent. 1 dwg, 6 tbl

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RU 2 153 878 C1

Authors

Sadzhaja L.A.

Vasilenko Ju.K.

Kompantseva E.V.

Moskalenko S.V.

Frolova L.M.

Parfent'Eva E.P.

Dates

2000-08-10Published

1999-04-27Filed