ANTITUBERCULAR RECTAL SUPPOSITORIES Russian patent published in 2004 - IPC

FIELD: chemicopharmaceutical industry. SUBSTANCE: the suggested medicinal form suppositories contains as active components, g: ethionamide 0.175, isoniazide 0.175, pyridoxine hydrochloride 0.03 and, also, complex fatty foundation 2.62. The present innovation enables to avoid inactivation of preparations with gastro-intestinal enzymes, hepatic metabolism and unfavorable action upon the body. Combination of isoniazide of high bacteriostatic activity and ethionamide that increases therapeutic effect of isoniazide and affect refractory and atypical forms of tubercular mycobacteria enables to decrease therapeutic doses of preparations applied. EFFECT: higher efficiency of application. 1 tbl