FIELD: medicine. SUBSTANCE: invention relates to production of the curative preparation made of donor blood plasma or serum. Method involves the successive treatment of the precipitate II + III obtained in alcohol fractionation of donor blood plasma or serum with aerosil A-380 and sodium caproate with intermediate centrifugations stages to remove inert proteins followed by ultrafiltration to remove low-molecular impurities and concentrating. After sterilizing filtration the end product is prepared that has an average 15% of IgM of total immunoglobulin content. EFFECT: increased content of immunoglobulin IgM in concentrate. 1 tbl, 1 ex
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