FIELD: medicine. SUBSTANCE: preparation is administered per os and is capable of rapid disintegration. The preparation has ondasteron as free base or pharmaceutically permissible solvate and one or several pharmaceutically permissible excipients. The advantageous quantity of ondasteron relative to free base is equal to 0.1-10% from composition mass. Method involves acting upon 5HT3 receptors with the suggested composition. The states like nausea and vomiting are the particular indications to drug application. Dose forms have no bitter taste inherent in forms containing ondasteron dihydrochloride dihydrate. EFFECT: enhanced effectiveness in treating mammals including human beings; accelerated absorption. 7 cl, 10 tbl
