FIELD: medicine; bioengineering. SUBSTANCE: method involves producing recombinant polypeptide possessing SCCE activity by culturing mouse cells C127 transformed with expression vector containing nucleotide sequence (SEQ IDN1) encoding the polypeptide. 0.001-25% of native or recombinant SCCE is included into the pharmaceutical composition for treating disorders related to keratinization. EFFECT: improved method for producing enzyme of high activity with respect to skin cornea layer. 7 cl, 36 dwg, 5 tbl
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1996 |
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RU2157847C2 |
| ANTIGEN OF HELICOBACTER PYLORI AND VACCINE COMPOSITION |
1996 |
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1994 |
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1996 |
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1994 |
- Lajmehn Stjuart D.
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1997 |
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2011 |
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1998 |
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RU2238976C2 |
