FIELD: organic chemistry, medicine, oncology. SUBSTANCE: method of treatment involves administration in human of effective dose of compound of the formula: 
where R1 and R3 mean independently -CH3, 
-alkyl or 
-Ar where Ar means optionally substituted phenyl; R2 is taken among the group containing pyrrolidino-, hexamethyleneimino- and piperidino-group, or its pharmaceutically acceptable salt or solvent. Preferable salt is hydrochloride. Preferable compound is reloxifen of the formula: 
or its hydrochloride. Compounds can be administrated by percutaneous route or as the dosed sustained-release form and by other known ways. Invention can be used for prophylaxis and treatment of patients with endometrial cancer. EFFECT: broadened arsenal of agents used for prophylaxis and treatment of endometrial cancer. 4 cl, 3 tbl, 12 ex
