AGENT FOR BLOOD CHOLESTEROL CONTENT DECREASE, PHARMACEUTICAL COMPOSITION Russian patent published in 1998 - IPC

Abstract RU 2123335 C1

FIELD: organic chemistry, medicine, pharmacology. SUBSTANCE: invention proposes a compound of the formula (I) for new application where n = 0 or 1; R is hydroxy-group, methoxy-group, (C1-C7)-alkanoylhydroxy-group, (C3-C7)-cycloalkanoyl- -hydroxy-group, (C1-C6)-alkoxy-(C1-C7)-alkanoylhydroxy-group, free or substituted aroylhydroxy-group or free or substituted aroyl- -carboxy-group; R1 is hydrogen atom, hydroxy-group, halogen atom, methoxy-group, (C1-C7)-alkanoylhydroxy-group, (C3-C7)-cycloalka- -noylhydroxy-group, (C1-C6)-alkoxy-(C1-C7)-alkanoylhydroxy-group, free or substituted aroylhydroxy-group or free or substituted aroylcarboxy-group; R2 is heterocyclic ring taken from the group involving pyrrolidine, piperidine or hexamethyleneimine group, or its pharmaceutically acceptable salt or solvate used for decrease of blood cholesterol content. Invention proposes a pharmaceutical composition for the same aim based on compound of the general formula (I). EFFECT: broadened pattern of hypocholesterolemic agents. 5 cl, 7 tbl

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RU 2 123 335 C1

Authors

Lehrri Dzhon Blehk

Khenri Ulman Brajant

Dzhordzh Dzhozef Kullinan

Rajmond Frehnsis Kauffman

Dates

1998-12-20Published

1993-12-13Filed