OCTA-4,5-CARBOXYLIC ACID PHTHALOCYANINE COBALT ESTERS, THEIR INCLUSION COMPLEXES WITH BETA-CYCLODEXTRIN PROPYLENE GLYCOL ESTER AND METHOD OF SUPPRESSION OF TUMOR GROWTH Russian patent published in 2001 - IPC

FIELD: organic chemistry, medicine, oncology. SUBSTANCE: invention relates to substances used in combination with ascorbic acid for therapy treatment of malignant neoplasma (binar catalytic "dark" therapy of malignant neoplasms) and method of suppression of tumor growth. Invention describes octa-4,5- carboxyphthalocyanine cobalt esters of the general formula (I) β- where R is or -CH₃O[CH₂CH₂O]_n; n = 3-7 and also their inclusion complexes with HO[CH₂CH₂O]_n-cyclodextrin propylene glycol ester and method of suppression of tumor growth using these compounds and ascorbic acid as a biogenic reducing agent. Use of proposed compounds provides the permanent and biologically significant inhibition of tumor growth and significant increase of mean spanlife of mice with transplanted malignant tumor of different genesis. EFFECT: enhanced antitumor effectiveness of compounds. 3 cl, 4 tbl, 10 ex