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2 186 765

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IPC

(21) (22)

Application

99118590/04, 1998-01-09

(24)

Start date

1998-01-09

(22)

Actual filing date

1998-01-09

(45)

Published

2002-08-10

(72)

Inventor

Kucher BerngardLandgraf Karl-FridrikhMejzel' PeterOl'Brikh Al'FredRisher MattiasTil' Vil'FridShefer Jurgen

(73)

Holder

Viatris Gmbkh Und Ko. Kg.

CRYSTALLINE MODIFICATIONS OF 2-AMINO-4-(4-FLUORO- -BENZYLAMINO)-1-ETHOXYCARBONYLAMINOBENZENE AND METHOD OF THEIR PREPARING (VARIANTS) Russian patent published in 2002 - IPC

Abstract RU 2186765 C2

FIELD: organic chemistry, medicine, pharmacy. SUBSTANCE: invention describes 2-amino-4-(4-fluorobenzylamino)-1-ethoxycarbonylaminobenzene of the formula (I) as crystalline modifications A, B and C. Each modification shows a diffraction roentgenogram with reflexes no coinciding with reflexes of two other modifications. Crystalline modifications A, B, C are designated for preparing pharmaceutical compositions with anticonvulsive, antipyretic and analgetic effect. Invention describes also methods of preparing the indicated modifications. EFFECT: improved method of preparing, valuable medicinal properties of compositions. 13 cl, 5 dwg

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RU 2 186 765 C2

Authors

Kucher Berngard

Landgraf Karl-Fridrikh

Mejzel' Peter

Ol'Brikh Al'Fred

Risher Mattias

Til' Vil'Frid

Shefer Jurgen

Dates

2002-08-10—Published

1998-01-09—Filed