NEW COMBINATION OF ANTI-HISTAMINE AGENTS HAVING NO SEDATIVE ACTION WITH COMPOUNDS EFFECTING TO LEUKOTRIEN ACTION FOR RHINITIS/CONJUNCTIVITIS TREATMENT Russian patent published in 2007 - IPC A61K31/55 A61K45/06 A61P37/08 A61P11/00 A61P11/02 A61P11/06

Abstract RU 2292208 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to pharmaceutical preparation and drug for topical administration useful in treatment of allergic and/or vasomotor rhinitis, respectively vasomotor conjunctivitis. Claimed preparation contains 50-500 mug of azelastine, 100-2000 mug of, such as leukotrien D4 antagonist (e.g., montelucast, zafirlucast, or pranlucast) or 5-lypoxigenase inhibitor (e.g., zyleuton, pipipost or AWD 23-115) and conventional pharmaceutically acceptable carriers. Method for production of abovementioned preparation also is disclosed.

EFFECT: pharmaceutical preparation and drug having accelerated and prolonged therapeutic effect and improved therapeutic efficiency due to synergic action of disclosed composition.

11 cl, 3 ex, 2 tbl

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RU 2 292 208 C2

Authors

Kuss Khil'Degard

Ehngel' Jurgen

Shelenyj Ishtvan

Dates

2007-01-27—Published

2001-02-05—Filed