FIELD: medicine, immunology, pharmacy. SUBSTANCE: invention claims composition comprising antibody raised against AILIM (alternatively named as JTT-antigen, JTT-2-antigen, ICOS and 8F4) that shows significant therapeutic effect against arthrosis, for example, rheumatic arthritis and osteoarthritis, transplant disease against host, immune rejection of transplant, inflammation (hepatitis and intestine inflammatory diseases), pathological state accompanying with excessive production of antibodies against foreign antigen triggered by antigen in immunological sensibilization. Invention provides preparing composition without adverse effects. EFFECT: valuable medicinal properties of composition. 24 cl, 52 dwg
