THYROID HORMONE-CONTAINING PHARMACEUTICAL COMPOSITION Russian patent published in 2003 - IPC

FIELD: medicine, endocrinology, pharmacy. SUBSTANCE: invention relates to the medicinal preparation acting on the thyroid gland function, namely, to thyroid hormone L-thyroxine. Pharmaceutical composition comprises the following components, mas. p. p. per unit mass of L-thyroxine: L-thyroxine sodium salt, the therapeutically effective dose; lactose, 84.6-112.3; modified lactose, 767.9-974.5; stearate, 4.5-10.5. Ratio of lactose to modified lactose = (0.08-0.15) : 1. Pharmaceutical composition is made as tablet mainly. Prepared L-thyroxine-containing tablets comprise reduced amount of accessory substances as measure for 1 g of L-thyroxine, they satisfy to all requirements of the State Pharmacopoeia, XI edition and they fitness time is 2 years, not less. EFFECT: improved and valuable properties of composition. 7 cl, 1 tbl