FIELD: therapeutic methods. SUBSTANCE: invention relates to system for delivering drugs, preferably in the form of ring suitable for vaginal introduction in order to simultaneously release progestogen steroid compound and estrogen steroid compound in fixed physiologic proportion during prolonged period of time. System includes at least one compartment to hold thermoplastic polymer core containing mixture of progestogen and estrogen compounds and thermoplastic coating, said progestogen compound being dissolved in polymer matrix of core in relatively low supersaturation degree. EFFECT: enabled prolonged drug release. 12 cl, 4 dwg, 2 tbl, 5 ex
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Authors
Dates
2003-06-20—Published
1998-04-09—Filed